CBD Hemp Oil – What You Need to Know
Hemp (Cannabis Sativa L.) is an annual herbal, fiber and oil plant originated from Central Asia and presently grown in many parts of the world. Hemp seeds are rich in oils and proteins and they are used for food.
The substrate set in the hemp blossom is called phytocannabinoid and has long been appreciated and researched for its therapeutic and protective effects on the central and peripheral nervous system (Lu et al., 2017). Different sources say that about 60 to 80 and up to 140 naturally occurring phytocannabinoids are found in hemp. CBD (Cannabidiol) and THC (Δ9-THC tetrahydrocannabinol) are the most commonly found cannabinoids.
The therapeutic use of cannabinoids still raises ethical issues today. In some countries the cultivation of cannabis and the extraction of cannabinoids without a specific authorization are prohibited because of psychoactive effect of the THC. THC stimulates the brain cells that emit dopamine hence causing a sense of pleasure and even euphoria; consequently THC has been classified as a narcotic. On the other hand, the use of cannabinoids including THC for recreational purposes is legal in some countries because of the lack of data in regards to the occurrence of addiction (Carnevale et al., 2017).
According to the WHO ECDD’s July 2018 recommendations, CBD should not be controlled because no psychotropic effects were identified in Cannabidiol. CannabiGold CBD has no THC in hemp oil, so this oil does not have any psychoactive effect. Therapeutic mechanisms for the treatment of cannabinoids have not been fully investigated, but they are known to work through the human endocannabinoid system, which includes endocannabinoids, cannabinoid receptors and endocannabinoid metabolism (Battista et al., 2006).
Numerous scientific studies note that the full spectrum of natural phytocannabinoid extracts and oils is more effective than medicines made from isolated cannabinoids. By using full-spectrum natural phytocannabinoids, the therapeutic effect can be felt with significantly lower doses of CBD. This can be explained by the presence of various phytochemicals in the different substances contained in the cannabis extract interacting with each other and reinforcing the action of each of them in the body.
In conclusion, it can be argued that there is sufficient scientific evidence for the therapeutic adaptation of phytocannabinoids due to their neuroprotective, anti-convulsant, tumor growth inhibiting and analgesic effects. There is a need for further random and placebo-controlled experiments which will explore the possibilities of adapting the CBD and its pharmacological effects because so far many mechanism of action have not been revealed.
In conclusion, it can be argued that there is sufficient scientific evidence for therapeutic use of phytocannabinoids due to their neuroprotective and anti-convulsant applications, as well as their tumor-growth inhibiting and analgesic effects. More randomized and placebo-controlled experiments are needed to explore further the potential applications of CBD and its pharmacological effects as many of the mechanisms of Cannabidiol have not yet been discovered.
1. Lu Y, Anderson HD. Cannabinoid signaling in health and disease. Can J Physiol Pharmacol 2017;95(4):311-327.
2. Carnevale JT, Kagan R, Murphy PJ, Esrick J. A practical framework for regulating for-profit recreational marijuana in US States: Lessons from Colorado and Washington. Int J Drug Policy 2017;42:71-85.
3. Battista N, Fezza, F, Finazzi-Agro A, Maccarrone M. The endocannabinoid system in neurodegeneration. Ital J. Biochem 2006;55(3–4):283–289.